The Obesity Guide Podcast with Matthea Rentea MD

Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. 

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The Obesity Guide Podcast with Matthea Rentea MD

Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. 
166. GLP-1s at Every Age: What You Should Actually Be Watching For Mar 30, 2026
 

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When it comes to GLP-1 medications, your age and stage of life matter more than a lot of people realize. What works for your body at 25 won't work the same way at 45... and definitely not at 65.

Yet somehow, most people are still being treated with a...

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165. How Your Nervous System Hijacks Your Eating (and How to Get It Back) with Jane Pilger Mar 23, 2026
 

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For 25 years, Jane Pilger couldn't figure out why she couldn't stop binge eating. She tried everything. And nothing stuck, until she uncovered the one piece no one had ever explained to her.

It had nothing to do with willpower… or food. It was her ne...

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164. Jacqui Cook on GLP-1 Weight Loss, Maintenance Fears, and Letting Go of Diet Rules Mar 16, 2026
 

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For decades, Jacqui Cook lived in a cycle many women know all too well: losing weight, gaining it back, and starting over… always wondering why nothing seemed to stick. Food was her love language, life kept getting in the way, and no matter how hard s...

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163. You've Hit Your Goal Weight…Now What? 5 Truths About Long-Term Weight Maintenance Mar 09, 2026
 

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You hit your goal weight. So now what?

For a lot of people, maintenance feels like uncharted territory. And without the right mindset, it's easy to either white-knuckle it or slowly drift back to old patterns. 

In this episode, I walk through five t...

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162. GLP-1s and Vision Loss: Separating Fact from Fear with Dr. Mina Farahani Mar 02, 2026
 

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There’s a lot of noise online about semaglutide, sudden vision loss, and scary eye complications. If you’re taking a GLP-1 (or thinking about it), you might be wondering:

Am I putting my vision at risk?

In a recent conversation with Dr. Mina Farahan...

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161. Restarting GLP-1s? 5 Reasons It Feels Harder This Time Feb 23, 2026
 

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You stopped your GLP-1 medication… maybe because of cost, side effects, or because things were finally going well and you thought, “I’ve got this now.” But then the weight started creeping back on, you went back on the medication… and now it’s just no...

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160. Perimenopause, GLP-1s, and What's Actually Affecting Your Sex Drive with Dr. Kristen Wolfe Feb 16, 2026
 

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If your sex drive has disappeared lately, you’re not alone. And you’re certainly not broken.

Between GLP-1 medications, perimenopause or menopause, postpartum changes, and the sheer mental load of modern life, many women notice their libido shift or ...

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159. Understanding PCOS: From Diagnosis to Long-Term Health with Dr. Sabrina Huq Feb 09, 2026
 

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If you’ve been told you have PCOS (or you suspect you might), you’ve probably been left with more questions than answers. It’s one of the most misunderstood conditions out there, and far too many people are misdiagnosed, under-treated, or given the sa...

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158. The Cost of GLP-1s is Forcing Switches: Can You Maintain Your Results? Feb 02, 2026
 

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What happens when the medication that's finally helping you is no longer affordable?

If you've had success on Mounjaro or Zepbound but need to switch to a more affordable option like Ozempic for maintenance, you're probably wondering: will this actua...

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157. Weight Loss Stalled on GLP-1? Focus On THIS Instead Jan 26, 2026
 

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Some of the best conversations start with listener questions, especially the ones that come from feeling stuck, confused, or wondering, 'is this normal?'

Today, I want to tackle two listener questions I received that I think a lot of you will relate ...

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156. Oral Wegovy: How to Take It, Who It's For, and What It Costs with Joseph Zucchi, PA Jan 19, 2026
 

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We finally have the first-ever FDA-approved oral GLP-1 for the treatment of obesity, and it's a much bigger deal than the headlines suggest.

I recently sat down with Joseph Zucchi, PA, a clinical supervisor at a medical weight management clinic who t...

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155. 200-Pound Weight Loss: Why Self-Love Is a Practice, Not a Feeling with Dr. Joy Bracey Jan 12, 2026
 

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Self-love is one of those phrases everyone recognizes… and almost no one feels confident they truly understand.

For some, it sounds like positive affirmations or surface-level self-care. For others, it feels vague, indulgent, or disconnected from rea...

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